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First-in-human trial of CRISPR gene-editing therapy safely lowered cholesterol, triglycerides
November 08, 2025
DALLAS, Texas, Nov. 8 [Category: Health Care] -- The American Heart Association posted the following news release:

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First-in-human trial of CRISPR gene-editing therapy safely lowered cholesterol, triglycerides

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Research Highlights:

* In a Phase 1, first-in-human trial, a one-time infusion of an investigational CRISPR-Cas9 therapy targeting angiopoietin-like protein 3 (ANGPTL3) was safe and reduced LDL cholesterol by nearly . . .

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