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Immune cells key in blood vessel damage, neurodegeneration
September 19, 2024
ITHACA, New York, Sept. 19 -- Cornell University issued the following news:

A new study helps explain why having ApoE4 the gene variant most closely linked to Alzheimer's disease increases the risk of neurodegeneration and white matter damage.

Researchers at Weill Cornell Medicine discovered that immune cells in the brain called border-associated macrophages (BAMs) are a source of ApoE4 protein and contribute to damaging blood vessels and brain tissue.

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